General Cognition and Alteration in Self-experiences in Schizophrenia Abnormal Self-experiences (ASEs) are prevalent in patients with schizophrenia, even though it is considered a primary alteration in this mental illness. Although understanding of these abnormal experiences is still poor, it seems conceivable that those ASEs may be related to other altered functions in psychosis that require…
Our colleague, Dr. Antonio Arjona, tells us his latest results on the alteration of Corolary Discharge in patients with schizophrenia: The term Corollary Discharge (CD) is used in the field of neuroscience to refer to copies of motor commands that allow our brain to predict the sensations generated by the execution of our own actions….
One of our main research lines is the alterations of the Self experience in schizophrenia. Today, our colleague Isabel Santos, a psychiatry resident at the Hospital Clínico Universitario de Valladolid, has reviewed the following article on this topic: “Self-disorders and the Schizophrenia Spectrum: A Study of 100 First Hospital Admissions” by Julie Nordgaard and Josef…
Today our PhD candidate Maria Iglesias, resident of neurophysiology at the University Hospital of Valladolid, has shown her bibliographic review on power alterations in different frequency bands (time-frequency analysis) in patients with schizophrenia or bipolar disorder during resting state. Recently Dr. Iglesias and Dr. Diez showed us their own results of alterations in EEG power…
Bibliographic session by Dr. Óscar Martín: Characterization of different cognitive groups in schizophrenia. Cognitive deficits are essential in characterising schizophrenia spectrum disorders. However, at present there is no pharmacological or other treatment available that effectively treats these symptoms. Multiple studies have attempted to categorize distinct subgroups that perform similarly on cognitive tests. The definition and…
Today, Professor Molina also briefly presented the preliminary analyses on the relationship between abnormal experiences of the Self and the anatomical data of those brain regions normally most involved in its generation. We found a high positive correlation coefficien between the thinning of the cortex in the caudal cingulate region and the intensity of those…
RESEARCH FINDINGS: ABNORMAL “SELF” PERCEPTIONS RELATED TO THE STATE OF BRAIN HIPERACTIVATION IN SCHIZOPHRENIA. In today’s session, our colleague Dr. Marta Hernández from the Hospital Clínico Universitario de Valladolid, presented her new research results on personal abnormal perceptions or “self” in patients with schizophrenia. These anomalous perceptions are alterations in the understanding of or relationship…
In line with our last session, today we made a review of the state of the scientific literature about identifying cognitive subgroups in the psychosis. The important heterogeneity given in the cognitive alterations in psychosis leads to the use of a more suitable approach: data-driven analyisis, instead of the classic predetermined methods used (i.e. diagnose)….
Today we have presented the preliminary results corresponding to the search for groups with biological significance, in our sample of patients with schizophrenia and bipolar disorder, based on their cognitive performance. We have included in this study 183 patients, 158 of them with schizophrenia and 25 with bipolar disorder, and 116 healthy controls. First, we…
