Literature review: Overcoming Rest–Task Divide—Abnormal Temporospatial Dynamics and Its Cognition in Schizophrenia (Northoff & Gomez-Pilar, 2020) Two of the most relevant findings in schizophrenia during the performance of an oddball paradigm are abnormal resting activity and reduced activity during task performance. These alterations are studied independently in numerous papers, but current evidence regarding the relationship…
AUDITORY EVOKED POTENTIALS, CONSEQUENT DISCHARGE AND ANOMALOUS EXPERIENCES OF THE SELF. Communication between two neural groups depends on the coherence or synchrony of neural activity between them (Fries, 2005). Ford et al. (2002) found that during speech generation, in healthy people, there was greater coherence between frontal and temporal regions in all frequency bands compared…
LITERATURE REVIEW. Watch it on Youtube here. Presented by Dr. Óscar Martín from Hospital Clínico Universitario de Valladolid. We analyzed the article “Understanding Cortical Dysfunction in Schizophrenia With TMS/EEG ” (Vittala A. et al,Front Neurosci. 2020 May). The combination of Transcranial Magnetic Stimulation and Electroencephalogram ( TMS-EEG) offers a unique opportunity to directly test a…
LITERATURE REVIEW. Watch it on YouTube here. Professor Vicente Molina performs the review of the following article: Treatment response after 6 and 26 weeks is related to baseline glutamate and GABA levels in antipsychotic-naïve patients with psychosis (Bojesen et al, 2019, Psychological Medicine) In this article, the authors investigate the possibility of predicting response to…
SCIENTIFIC PAPER REVIEW: Neuroimaging Heterogeneity in Psychosis: Neurobiological Underpinnings and Opportunities for Prognostic and Therapeutic Innovation (Voineskos et al., 2019) Below, Dr. Antonio Arjona, postdoctoral researcher, presents a summary of his scientific review. Currently, one of the main objectives of researchers in relation to the diagnosis of mental disorders is to identify reliable biomarkers. The…
ANOMALOUS EXPERIENCES OF THE SELF AND CONSEQUENT DISCHARGE IN SCHIZOPHRENIA. STATUS OF OUR PROJECT BY ROSA BEÑO (PHD CANDIDATE). Corollary discharge (CD) has been studied in several sensory-perceptual phenomena. This is a mechanism used to distinguish self-generated perceptions from those coming from external sources, allowing us to label the sensations that come from acts generated…
Today our colleague from the Hospital Clínico Universitario de Valladolid, Dr. Óscar Martín, summarizes his literature review of the article: “Heterogeneity of Striatal Dopamine Function in Schizophrenia: Meta-analysis of Variance” (Stefan P. Brugger et al.; Biol Psychiatry, 2020). Alterations of dopamine function in schizophrenia have been proven since the beginning of neuroleptic treatment in the…
JOURNAL CLUB: NEURONAL NETWORKS AND COGNITIVE ALTERATIONS IN PSYCHIATRIC DISORDERS (EVA RODRÍGUEZ VÁZQUEZ MIR-IV PSYCHIATRY HCUV) It has long been assumed that cognitive functions are attributed to isolated brain areas. In the last decade, more and more studies have been based on the idea that cognition is the result of dynamic interactions of brain areas…
ALTERATIONS IN EEG ACTIVITY DURING AN N-BACK TASK IN SCHIZOPHRENIA (DR. ANTONIO ARJONA) In the last two decades there has been a significant increase in the number of publications that highlight deficits in working memory as a central factor within the cognitive symptomatology associated with schizophrenia (Sz). However, there is still a wide lack of…
Today our colleague Rosa Beño summarizes and presents a key review on Speaking-Induced Suppression (SIS), key to understand the alterations of the self in patients with schizophrenia. BILIOGRAPHIC REVIEW: Whitford, T. J. (2019). Speaking-induced suppression of the auditory cortex in humans and its relevance to schizophrenia. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(9), 791-804. …
