FMRI RESULTS AT REST AND ABNORMAL EXPERIENCES OF THE SELF IN SCHIZOPHRENIA (BY ALEJANDO ROIG)
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In this video an explanation is carried out on the possible relationship between the default mode network and abnormal experiences of the self in schizophrenia. The default mode network is a set of brain areas that have joint activity when one is not performing any task or “minding one’s own business”. On the other hand, abnormal self experiences are bizarre ways of perceiving and feeling oneself and one’s relationship to the world, being a characteristic feature of some people with schizophrenia.
In our study, default mode network activity has been analyzed through correlation analysis of functional magnetic resonance imaging of patients. Abnormal experiences of the self have been explored through the IPASE inventory. The results show a positive correlation between IPASE scores and hyperconnectivity of the parahippocampal cortex. Specifically, with the regions of the anterior cingulate cortex and the cingulate isthmus cortex. That is, the greater the joint activity of these regions, the more abnormal experiences of the self.