In our latest group meeting, the SUCEDE team gathered to analyze a study recently published in the prestigious journal Nature (within its specialized schizophrenia section). On this occasion, our colleague R. Beño led the session, presenting a paper that explores the complex relationship between neurotransmitter levels and electrophysiological markers within the psychosis spectrum. GABA Levels…
Video link @ SUCEDE YouTube Channel In our latest working session, the SUCEDE research group presented an update on the integrity of inhibitory circuits in patients with psychosis. By combining Transcranial Magnetic Stimulation (TMS) and Electroencephalography (EEG), we are successfully “mapping” the neurochemical balance of the prefrontal cortex with unprecedented precision. The Challenge: Measuring GABA…
On February 5 and 6, 2026, the Faculty of Medicine at the University of Valladolid (UVa) hosted the VII International Conference on Updates in Schizophrenia. Supported by funding from the Fundación La Marató de TV3, this edition focused on the transition “From Cortical and Self-Experience Dysfunction to Subtypification” within the spectrum of psychosis. Advances in…
Is it possible to objectively measure the level of integration and differentiation of brain activity in psychosis? Dr. Vicente Molina, Principal Investigator of SUCEDE, shared the group’s most recent findings using a combination of cutting-edge techniques: Transcranial Magnetic Stimulation combined with Electroencephalography (TMS/EEG). The focus of this presentation lies on the Perturbational Complexity Index (PCI)…
The understanding of schizophrenia has evolved from mere symptomatic observation toward the search for biological substrates that explain the alteration of the “Self.” In our latest seminar session, Antonio Arjona, a researcher at SUCEDE, presented the most recent advances in his project focused on corollary discharge (CD) and readiness potential. Corollary discharge is an essential…
Emma Osorio, SUCEDE predoctoral researcher, reviews ‘Prefrontal Oscillatory Slowing in Early-Course Schizophrenia Is Associated With Worse Cognitive Performance and Negative Symptoms: A Transcranial Magnetic Stimulation–Electroencephalography Study’ (Donati et al., 2024). In clinical practice, schizophrenia remains a diagnostic and therapeutic challenge, particularly regarding cognition and negative symptoms. Recently, the SUCEDE group presented a bibliographic session analyzing…
REGISTER HERE On February 5th and 6th, 2026, the Faculty of Medicine at the University of Valladolid (UVa) will host a key debate on the latest advances in schizophrenia research. Within the framework of “La Marató” Project, these VII Update Sessions offer a scientific journey ranging from cortical dysfunction to the search for biotypes based…
Neurophysiological Markers of the “Self” in Psychosis: Insights from the SUCEDE Project: As part of the ongoing dissemination of the SUCEDE project, we are sharing a synthesis of our current findings focused on the cerebral substrates of agency recognition and its alteration across the psychotic spectrum. Access the Audiovisual Document: https://youtu.be/MB5cFJMVYHY
Neuroconnectivity Analysis in Psychosis: Implications of PCI Results in the Delineation of Biotypes The session addressed the methodological application of the Perturbational Complexity Index (PCI) as an objective marker for patient stratification within the psychotic spectrum. The relevance of this research lies in the urgent need to transition from a symptomatic nosology toward an etiopathogenic…
Video in YouTube (in Spanish) 🧠 The Root of the Problem: Disturbance of the Minimal SelfFor more than a century, figures like Kraepelin and Bleuler already pointed out that the core of psychosis is not just the striking symptoms, but a profound alteration in the sense of Self. Bleuler, in fact, considered Self-Disturbances to be…
