Groupings of patients with schizophrenia and bipolar disorder based on EEG functional network measures (Vicente Molina and Alvaro Planchuelo) We have analyzed the possibility of describing biologically valid clusters of patients with schizophrenia and bipolar disorder based on the characteristics of their functional network derived from EEG recordings. We found two clusters: with this altered…
PATIENTS WITH GREATER HYPERACTIVATION AT RESTING STATE MODULATE THEIR BRAIN ACTIVITY LESS DURING A COGNITIVE TASK. EVIDENCE USING THE SPECTRAL ENTROPY MEASURE (Dr. María Iglesias and Dr. Álvaro Díez) Entropy is a thermodynamic function that was adapted to the context of information theory. Applied in the power spectrum of the EEG it is called Spectral…
BIBLIOGRAPHIC REVIEW: IMPAIRED COROLLARY DISCHARGE IN PSYCHOSIS AND AT-RISK STATES: INTEGRATING NEURODEVELOPMENTAL, PHENOMENOLOGICAL AND CLINICAL PERSPECTIVES (Poletti et al., 2019, Biol Psychiatry Cogn Neurosci Neuroimaging). In this article published in 2019 in Biol Psychiatry Cogn Neurosci Neurimaging, the authors (Michele Poletti, Antonio Tortorella and Andrea Raballo) start from the following conceptual framework: they understand the…
PRELIMINARY RESULTS: ALTERATIONS IN COROLLARY DISCHARGE IN SCHIZOPHRENIA Corollary discharge (CD) is a mechanism used to distinguish self-generated perceptions from those coming from external sources. To correctly make this distinction, a copy of the motor processing is sent to the sensory regions, predicting the sensory consequences that this motor act will generate. By comparing this…
General Cognition and Alteration in Self-experiences in Schizophrenia Abnormal Self-experiences (ASEs) are prevalent in patients with schizophrenia, even though it is considered a primary alteration in this mental illness. Although understanding of these abnormal experiences is still poor, it seems conceivable that those ASEs may be related to other altered functions in psychosis that require…
Our colleague, Dr. Antonio Arjona, tells us his latest results on the alteration of Corolary Discharge in patients with schizophrenia: The term Corollary Discharge (CD) is used in the field of neuroscience to refer to copies of motor commands that allow our brain to predict the sensations generated by the execution of our own actions….
One of our main research lines is the alterations of the Self experience in schizophrenia. Today, our colleague Isabel Santos, a psychiatry resident at the Hospital Clínico Universitario de Valladolid, has reviewed the following article on this topic: “Self-disorders and the Schizophrenia Spectrum: A Study of 100 First Hospital Admissions” by Julie Nordgaard and Josef…
Today our PhD candidate Maria Iglesias, resident of neurophysiology at the University Hospital of Valladolid, has shown her bibliographic review on power alterations in different frequency bands (time-frequency analysis) in patients with schizophrenia or bipolar disorder during resting state. Recently Dr. Iglesias and Dr. Diez showed us their own results of alterations in EEG power…
Bibliographic session by Dr. Óscar Martín: Characterization of different cognitive groups in schizophrenia. Cognitive deficits are essential in characterising schizophrenia spectrum disorders. However, at present there is no pharmacological or other treatment available that effectively treats these symptoms. Multiple studies have attempted to categorize distinct subgroups that perform similarly on cognitive tests. The definition and…
Today, Professor Molina also briefly presented the preliminary analyses on the relationship between abnormal experiences of the Self and the anatomical data of those brain regions normally most involved in its generation. We found a high positive correlation coefficien between the thinning of the cortex in the caudal cingulate region and the intensity of those…
