YouTube Video (in Spanish) Disconnection in Schizophrenia: The Key Lies in Brain Flexibility 🧠💡Our research group, SUCEDE, has reviewed years of pioneering work using Electroencephalography (EEG) and Neuropsychology to unravel the biological basis of Schizophrenia (SZ).The central finding is clear: schizophrenia appears to be a disorder of brain flexibility, manifested as a combination of basal…
YouTube video (in Spanish) In the field of psychiatry, a topic of constant debate has been the classification of schizophrenia. Is it a disease with a single symptom profile, or are there biologically distinct subtypes? The SUCEDE group reviewed an article that delves into this question, investigating whether auditory hallucinations, one of the most characteristic…
Video YouTube (in Spanish) At our kick-off meeting for the academic year, we’ve set the key goals that will guide our group’s work. A central focus is to deepen our understanding of psychosis biotypes, an effort to identify the underlying biological bases of this complex disorder. To advance this objective, we will continue to leverage…
Video (in Spanish): https://youtu.be/yWie7gOOIPU Antonio Arjona:The latest meeting of the SUCEDE research group focused on exploring the relationship between the segregation of resting-state brain activity and self-experience in patients with schizophrenia. Through the analysis of resting-state EEG data (64 electrodes) and the quantification of the clustering coefficient (CLC)—a measure of local brain connectivity—the study has…
Video in our YouTube channel Schizophrenia, a severe neuropsychiatric disorder, has driven extensive research into its neuronal underpinnings. In this context, functional network analysis, derived from graph theory, emerges as a robust methodology for investigating brain architecture and dynamics. This approach conceptualizes the brain as a complex network where brain regions act as nodes and…
Paper review: “Differential effects of illness and antipsychotics on cortical thinning in first episode psychosis: A randomised placebo-controlled MRI study” (Chopra et al., preprint) The current article, still in preprint, delves into the intricate relationship between psychosis, antipsychotic treatment, and structural brain modifications. This research specifically focused on cortical thinning in patients experiencing a first…
Paper review: “Schizophrenia, Consciousness, and the Self – Twenty Years Later: Revisiting the Ipseity-Disturbance Model and the Developmental Nature of Self-Disorder in the Schizophrenia Spectrum” (Raballo et al., 2025) Schizophrenia, a complex neuropsychiatric disorder, often manifests through abnormal self-experiences that transcend classic psychotic symptomatology. These delve into fundamental alterations of ipseity or the sense of…
Bibliographic review: “Fractal dimension analysis of resting state functional networks in schizophrenia from EEG signals” (Ruiz de Miras et al., 2023) Understanding resting-state brain activity is fundamental for unraveling the pathophysiology of various neuropsychiatric disorders. Recent research, presented by E. Osorio, addresses this field through the analysis of brain complexity using Fractal Dimension (FD) in…
Beño-Ruiz-de-la-Sierra et al. (Universidad de Valladolid): Fernandez-Linsenbarth et al. (Universidad de Valladolid):
Paper: Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia (JAMA Psychiatry; Pardiñas et al., 2022) This paper by Pardiñas et al. attempts to find possible polymorphisms with which to estimate whether a patient diagnosed with schizophrenia may present treatment resistance (TRS, treatment resistant schizophrenia),…
